Dear Colleague:

As research into the pathophysiologic processes in mild cognitive impairment (MCI) and Alzheimer’s disease progresses, treatment of patients is shifting from an emphasis on maintaining cognitive function and treating symptoms to one that also targets the underlying pathology. A key factor in this shift, however, is the ability of clinicians to accurately recognize and diagnose these conditions at the earliest possible time along the disease continuum. Clinical decisions made early in the process of care may thus potentially affect the progress of the disease.

The following case study is being provided as a prelude to an upcoming CME case-based lecture scheduled in your area. It previews the critical clinical questions and decisions involved in the management of a patient with MCI or Alzheimer’s disease. The rationale for the various management strategies employed in this case, as supported by current evidence-based medicine and results of recent clinical trials, will be discussed during the lecture.

This activity is designed to be interactive with questions posed at various critical decision points. Please answer the questions based on your current practice. Physicians will receive a maximum of 0.5 AMA PRA Category 1 Credit™ for participating in this activity.

Your participation in this preview activity will provide you with a glimpse of the lecture content and allow you to prepare questions in advance for the speakers who will be presenting the program in your community.

Thank you for participating in both the case study preview and the live lecture. I hope that these CME activities will help you to optimize the care of your patients with MCI or Alzheimer’s disease.

Sincerely,

George T. Grossberg, MD
Samuel W. Fordyce Professor
Director of Geriatric Psychiatry
Department of Neurology and Psychiatry
Saint Louis University School of Medicine
Saint Louis, Missouri